![]() ![]() Azithromycin in a single oral 1-g dose is now a recommended regimen for the treatment of nongonococcal urethritis. Valacyclovir and famciclovir are not yet recommended for use during pregnancy. Three antiviral medications have been shown to provide clinical benefit in the treatment of genital herpes: acyclovir, valacyclovir and famciclovir. Parenteral penicillin continues to be the drug of choice for treatment of all stages of syphilis. A three-day course of 500 mg of oral ciprofloxacin twice daily may be used to treat chancroid in patients who are not pregnant. Two single-dose regimens, 1 g of oral azithromycin and 250 mg of intramuscular ceftriaxone, are effective for the treatment of chancroid. Treatment advances include effective single-dose regimens for many sexually transmitted diseases and improved therapies for herpes infections. ![]() Part I of this two-part article describes current recommendations for the treatment of genital ulcer diseases, urethritis and cervicitis. Several treatment advances have been made since the previous guidelines were published. In 1998, the Centers for Disease Control and Prevention released guidelines for the treatment of sexually transmitted diseases.
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